GNE-6468

Modify Date: 2025-08-27 10:38:11

GNE-6468 Structure
GNE-6468 structure
Common Name GNE-6468
CAS Number 1677668-27-7 Molecular Weight 433.84
Density N/A Boiling Point N/A
Molecular Formula C23H16ClN3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GNE-6468


GNE-6468 is a potent and selective RORγ(RORc) agonists with an EC50 value of 13 nM for HEK-293 cell.

 Names

Name GNE-6468

 GNE-6468 Biological Activity

Description GNE-6468 is a potent and selective RORγ(RORc) agonists with an EC50 value of 13 nM for HEK-293 cell.
Related Catalog
References

[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.

 Chemical & Physical Properties

Molecular Formula C23H16ClN3O4
Molecular Weight 433.84
InChIKey GIYKJPISDNWSJD-UHFFFAOYSA-N
SMILES O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C3CC3)n3cccnc23)cc1O
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