APJ receptor agonist 6

Modify Date: 2025-08-22 09:22:42

APJ receptor agonist 6 structure	Common Name	APJ receptor agonist 6
	CAS Number	1965244-85-2	Molecular Weight	523.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₄FN₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of APJ receptor agonist 6

APJ receptor agonist 6 (compound 9) is a potent APJ (apelin receptor) agonist, with Ki of 1.3 μM. APJ receptor agonist 6 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively[1].

Name	APJ receptor agonist 6

Description	APJ receptor agonist 6 (compound 9) is a potent APJ (apelin receptor) agonist, with Ki of 1.3 μM. APJ receptor agonist 6 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease
Target	EC50: 0.800 ± 0.1 μM (Apelin Receptor calcium), 0.844 ± 0.2 μM (Apelin Receptor cAMP), 6.22 ± 2.0 μM (Apelin Receptor β-arrestin), >10 μM (AT1 calcium)[1]
References	[1]. Narayanan S, et al. Identification of potent pyrazole based APELIN receptor (APJ) agonists. Bioorg Med Chem. 2020 Feb 15;28(4):115237.

Molecular Formula	C₂₉H₃₄FN₃O₅
Molecular Weight	523.60

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APJ receptor agonist 6

Use of APJ receptor agonist 6

Names

APJ receptor agonist 6 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.