APJ receptor agonist 5

Modify Date: 2024-01-12 21:44:11

APJ receptor agonist 5 Structure
APJ receptor agonist 5 structure
Common Name APJ receptor agonist 5
CAS Number 2135514-20-2 Molecular Weight 479.52
Density N/A Boiling Point N/A
Molecular Formula C26H29N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of APJ receptor agonist 5


APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease[1].

 Names

Name APJ receptor agonist 5

 APJ receptor agonist 5 Biological Activity

Description APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease[1].
Related Catalog
References

[1]. Meng W, et al. Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure. J Med Chem. 2021;64(24):18102-18113.

 Chemical & Physical Properties

Molecular Formula C26H29N3O6
Molecular Weight 479.52
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

APJ receptor agonist 5 suppliers

APJ receptor agonist 5 price