APJ receptor agonist 7

Modify Date: 2024-01-14 10:55:39

APJ receptor agonist 7 structure	Common Name	APJ receptor agonist 7
	CAS Number	2100850-28-8	Molecular Weight	550.73
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₂H₄₆N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of APJ receptor agonist 7

APJ receptor agonist 7 (compound 37) is a potent and orally active APJ (apelin receptor) agonist, with Ki of 0.059 μM. APJ receptor agonist 7 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively[1].

Name	APJ receptor agonist 7

Description	APJ receptor agonist 7 (compound 37) is a potent and orally active APJ (apelin receptor) agonist, with Ki of 0.059 μM. APJ receptor agonist 7 has EC50 values of 0.070 , 0.097, and 0.063 μM for calcium, cAMP, and β-arrestin, respectively[1].
Related Catalog	Research Areas >> Cardiovascular Disease
Target	EC50: 0.063 ± 0.004 μM (Apelin Receptor β-arrestin), 0.070 ± 0.009 μM (Apelin Receptor calcium), 0.097 ± 0.032 μM (Apelin Receptor cAMP), >10 μM (AT1 calcium)[1]
References	[1]. Narayanan S, et al. Identification of potent pyrazole based APELIN receptor (APJ) agonists. Bioorg Med Chem. 2020 Feb 15;28(4):115237.

Molecular Formula	C₃₂H₄₆N₄O₄
Molecular Weight	550.73

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APJ receptor agonist 7

Use of APJ receptor agonist 7

Names

APJ receptor agonist 7 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.