Tos-PEG5-CH2CO2H

Modify Date: 2024-01-22 11:26:57

Tos-PEG5-CH2CO2H Structure
Tos-PEG5-CH2CO2H structure
Common Name Tos-PEG5-CH2CO2H
CAS Number 2028284-73-1 Molecular Weight 406.45
Density N/A Boiling Point N/A
Molecular Formula C17H26O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG5-CH2CO2H


Tos-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tos-PEG4-CH2COOH
Synonym More Synonyms

 Tos-PEG5-CH2CO2H Biological Activity

Description Tos-PEG4-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

 Chemical & Physical Properties

Molecular Formula C17H26O9S
Molecular Weight 406.45

 Synonyms

MFCD30458013