m-PEG3-Sulfone-PEG4-propargyl

Modify Date: 2024-01-03 10:15:20

m-PEG3-Sulfone-PEG4-propargyl Structure
m-PEG3-Sulfone-PEG4-propargyl structure
Common Name m-PEG3-Sulfone-PEG4-propargyl
CAS Number 2055041-02-4 Molecular Weight 426.52
Density N/A Boiling Point N/A
Molecular Formula C18H34O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG3-Sulfone-PEG4-propargyl


m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG3-Sulfone-PEG4-propargyl
Synonym More Synonyms

 m-PEG3-Sulfone-PEG4-propargyl Biological Activity

Description m-PEG3-Sulfone-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H34O9S
Molecular Weight 426.52

 Synonyms

MFCD29918252
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