DBCO-PEG4-triethoxysilane

Modify Date: 2024-01-15 18:50:26

DBCO-PEG4-triethoxysilane Structure
DBCO-PEG4-triethoxysilane structure
Common Name DBCO-PEG4-triethoxysilane
CAS Number 2353410-02-1 Molecular Weight 755.97
Density N/A Boiling Point N/A
Molecular Formula C39H57N3O10Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG4-triethoxysilane


DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG4-triethoxysilane

 DBCO-PEG4-triethoxysilane Biological Activity

Description DBCO-PEG4-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C39H57N3O10Si
Molecular Weight 755.97