ENPP1 Inhibitor C

Modify Date: 2024-01-09 18:31:14

ENPP1 Inhibitor C Structure
ENPP1 Inhibitor C structure
Common Name ENPP1 Inhibitor C
CAS Number 2378640-92-5 Molecular Weight 282.344
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C15H18N6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ENPP1 Inhibitor C


Enpp-1-IN-2 (Compound C) is a potent ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC50 values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. TG (Tokyo Green)-mAMP: a newly synthesized sensitive ENPP1 fluorescence probe[1].

 Names

Name ENPP1 Inhibitor C
Synonym More Synonyms

 ENPP1 Inhibitor C Biological Activity

Description Enpp-1-IN-2 (Compound C) is a potent ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) inhibitor with IC50 values of 0.26, 0.48 and 2.0 μM evaluated by means of TG-mAMP, pNP-TMP, and ATP assays, respectively. TG (Tokyo Green)-mAMP: a newly synthesized sensitive ENPP1 fluorescence probe[1].
Related Catalog
Target

IC50: 0.26 μM (TG-mAMP assay), 0.48 μM (pNP-TMP assay), 2.0 μM (ATP assay)[1]

References

[1]. Kawaguchi M, et al. Development of an ENPP1 Fluorescence Probe for Inhibitor Screening, Cellular Imaging, and Prognostic Assessment of Malignant Breast Cancer. J Med Chem. 2019 Oct 24;62(20):9254-9269.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C15H18N6
Molecular Weight 282.344
Exact Mass 282.159302
LogP 1.10
Index of Refraction 1.679

 Synonyms

ENPP1 Inhibitor C
6-(3-Aminobenzyl)-N,N,5-trimethyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
[1,2,4]Triazolo[1,5-a]pyrimidin-7-amine, 6-[(3-aminophenyl)methyl]-N,N,5-trimethyl-