HIF-2α-IN-7

Modify Date: 2024-01-10 15:50:25

HIF-2α-IN-7 Structure
HIF-2α-IN-7 structure
Common Name HIF-2α-IN-7
CAS Number 2511247-29-1 Molecular Weight 385.26
Density N/A Boiling Point N/A
Molecular Formula C18H9F6NO2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HIF-2α-IN-7


HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC50 value of 6nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].

 Names

Name HIF-2α-IN-7

 HIF-2α-IN-7 Biological Activity

Description HIF-2α-IN-7 is a hypoxia inducible factor 2α (HIF-2α) inhibitor. HIF-2α-IN-7 can inhibit HIF-2α with an EC50 value of 6nM. HIF-2α-IN-7 can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].
Related Catalog
Target

EC50: 6nM (HIF-2α)[1]

In Vitro HIF-2α-IN-7 has inhibitory activity for HIF-2α with an EC50 value of 6nM[1].
References

[1]. Jiping Fu, et al. Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors. Patent. WO2020214853A1.

 Chemical & Physical Properties

Molecular Formula C18H9F6NO2
Molecular Weight 385.26