Mal-PEG2-NHS

Modify Date: 2024-01-09 08:06:34

Mal-PEG2-NHS Structure
Mal-PEG2-NHS structure
Common Name Mal-PEG2-NHS
CAS Number 329364-72-9 Molecular Weight 340.29
Density N/A Boiling Point N/A
Molecular Formula C14H16N2O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-PEG2-NHS


Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG2-NHS

 Mal-PEG2-NHS Biological Activity

Description Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H16N2O8
Molecular Weight 340.29