Mal-PEG2-alcohol
Modify Date: 2024-01-09 21:47:55
Mal-PEG2-alcohol structure
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Common Name | Mal-PEG2-alcohol | ||
|---|---|---|---|---|
| CAS Number | 34321-81-8 | Molecular Weight | 185.17700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H11NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mal-PEG2-alcoholMal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 1-[2-(2-hydroxyethoxy)ethyl]pyrrole-2,5-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Mal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C8H11NO4 |
|---|---|
| Molecular Weight | 185.17700 |
| Exact Mass | 185.06900 |
| PSA | 66.84000 |
|
~92%
Mal-PEG2-alcohol CAS#:34321-81-8 |
| Literature: Heredia, Karina L.; Bontempo, Debora; Ly, Tiffany; Byers, Joshua T.; Halstenberg, Sven; Maynard, Heather D. Journal of the American Chemical Society, 2005 , vol. 127, # 48 p. 16955 - 16960 |
|
~%
Mal-PEG2-alcohol CAS#:34321-81-8 |
| Literature: Raouane, Mouna; Desmaele, Didier; Gilbert-Sirieix, Marie; Gueutin, Claire; Zouhiri, Fatima; Bourgaux, Claudie; Lepeltier, Elise; Gref, Ruxandra; Ben Salah, Ridha; Clayman, Gary; Massaad-Massade, Liliane; Couvreur, Patrick Journal of Medicinal Chemistry, 2011 , vol. 54, # 12 p. 4067 - 4076 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| MFCD16780862 |