SIRT5 inhibitor 2

Modify Date: 2025-08-25 16:15:31

SIRT5 inhibitor 2 Structure
SIRT5 inhibitor 2 structure
Common Name SIRT5 inhibitor 2
CAS Number 340306-87-8 Molecular Weight 407.27
Density N/A Boiling Point N/A
Molecular Formula C18H12Cl2N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SIRT5 inhibitor 2


SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].

 Names

Name SIRT5 inhibitor 2

 SIRT5 inhibitor 2 Biological Activity

Description SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].
Related Catalog
Target

SIRT5:2.3 μM (IC50)

References

[1]. Wang Y, et al. Overview of SIRT5 as a potential therapeutic target: Structure, function and inhibitors. Eur J Med Chem. 2022;236:114363.

 Chemical & Physical Properties

Molecular Formula C18H12Cl2N2O3S
Molecular Weight 407.27
InChIKey NASLGRREAVKNNT-FMIVXFBMSA-N
SMILES C=CCN1C(=O)C(=Cc2ccc(-c3cccc(Cl)c3Cl)o2)C(=O)NC1=S
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