Tos-PEG8-Tos

Modify Date: 2024-01-09 22:15:08

Use of Tos-PEG8-Tos

Tos-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-[2-[2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
Synonym	More Synonyms

Description	Tos-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

3,6,9,12,15,18,...

CAS#:5117-19-1

Tosyl chloride

CAS#:98-59-9

~99%

Tos-PEG8-Tos

CAS#:57436-38-1

PROTAC Linker 16

CAS#:37860-51-8

Tos-PEG8-Tos

CAS#:57436-38-1

2,2'-((Oxybis(e...

CAS#:112-60-7

Tos-PEG8-Tos

CAS#:57436-38-1

1,1,1,27,27,27-...

CAS#:144270-98-4

Tos-PEG8-Tos

CAS#:57436-38-1

Precursor 4
CAS#:5117-19-1 3,6,9,12,15,18,... CAS#:98-59-9 Tosyl chloride CAS#:37860-51-8 PROTAC Linker 16 CAS#:112-60-7 2,2'-((Oxybis(e...
DownStream 1
CAS#:6790-09-6 PEG13

1,24-bis(tosyloxy)-3,6,9,12,15,18,21-heptaoxatetracosane

Octaethylene glycol di(p-toluenesulfonate)

Octaethylene glycol ditosylate

3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diyl bis(4-methylbenzenesulfonate)

1,23-bis(tosyloxy)-3,6,9,12,15,18,21-heptaoxatricosane

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