3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol

Modify Date: 2024-01-06 19:02:32

3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol Structure
3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol structure
Common Name 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol
CAS Number 5117-19-1 Molecular Weight 370.436
Density 1.1±0.1 g/cm3 Boiling Point 471.5±40.0 °C at 760 mmHg
Molecular Formula C16H34O9 Melting Point 22 °C
MSDS N/A Flash Point 239.0±27.3 °C

 Use of 3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol


Octaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name octaethylene glycol
Synonym More Synonyms

  Biological Activity

Description Octaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 471.5±40.0 °C at 760 mmHg
Melting Point 22 °C
Molecular Formula C16H34O9
Molecular Weight 370.436
Flash Point 239.0±27.3 °C
Exact Mass 370.220276
PSA 105.07000
LogP -3.66
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.463

 Safety Information

WGK Germany 3
HS Code 2909499000

 Synthetic Route

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

Octaethylene Glycol
EINECS 225-856-4
2-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD00698694
3,6,9,12,15,18,21-Heptaoxatricosane-1,23-diol
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