DPP-IV-IN-1 structure
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Common Name | DPP-IV-IN-1 | ||
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CAS Number | 625110-37-4 | Molecular Weight | 243.27800 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C11H18FN3O2 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of DPP-IV-IN-1DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM. |
Name | (2S,4S)-4-fluoro-1-{[(2-hydroxy-1,1-dimethylethyl)amino]acetyl}pyrrolidine-2-carbonitrile |
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Synonym | More Synonyms |
Description | DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM. |
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Related Catalog | |
In Vivo | DPP-IV-IN-1 (0.1 and 0.3 mg/kg, p.o.) reduces the increase in plasma glucose beginning 30 min after glucose loading, and significantly suppresses hyperglycemia at the dose of 0.3 mg/kg in a rat model of obesity and impaired glucose tolerance. The effect is based on its inhibitory effect on plasma DPP-IV activity[1]. |
References |
Molecular Formula | C11H18FN3O2 |
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Molecular Weight | 243.27800 |
Exact Mass | 243.13800 |
PSA | 76.36000 |
LogP | 0.13828 |
(2S,4S)-2-cyano-4-fluoro-1-[(2-hydroxy-1,1-dimethyl)ethylamino]acetylpyrrolidine |
DPP-IV-IN-1 |