Foscarnet sodium structure
|
Common Name | Foscarnet sodium | ||
---|---|---|---|---|
CAS Number | 63585-09-1 | Molecular Weight | 191.951 | |
Density | N/A | Boiling Point | 270-272°C | |
Molecular Formula | CNa3O5P | Melting Point | 62-65 °C(lit.) | |
MSDS | N/A | Flash Point | 270-272°C |
Use of Foscarnet sodiumFoscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3]. |
Name | trisodium phosphonoformate |
---|---|
Synonym | More Synonyms |
Description | Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3]. |
---|---|
Related Catalog | |
In Vitro | Foscarnet sodium (Trisodium phosphonoformate) inhibits Influenza A Victoria (IC50=29 μM), Influenza B HK (IC50=61 μM), and Avian myeloblastosis virus (IC50=5-8 μM),HSV-1, several strains (IC50=0.4-3.5 μM)[2]. |
References |
Boiling Point | 270-272°C |
---|---|
Melting Point | 62-65 °C(lit.) |
Molecular Formula | CNa3O5P |
Molecular Weight | 191.951 |
Flash Point | 270-272°C |
Exact Mass | 191.917648 |
PSA | 113.13000 |
Storage condition | -20℃ |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Hazard Codes | Xi |
---|---|
Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
Safety Phrases | S26-S36 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
Packaging Group | II |
HS Code | 2942000000 |
~0% Foscarnet sodium CAS#:63585-09-1 |
Literature: Noren; Helgstrand; Johansson; Misiorny; Stening Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 264 - 270 |
~% Foscarnet sodium CAS#:63585-09-1 |
Literature: Phosphorus, Sulfur and Silicon and the Related Elements, , vol. 51/52, p. 778 |
HS Code | 2942000000 |
---|
Phosphoranecarboxylic acid, 1,1-dihydroxy-, oxide, sodium salt (1:3) |
Trisodium dioxidophosphinecarboxylate oxide |
Foscanet sodium |
Triapten |
Foscarnet sodium |
phosphoranecarboxylic acid, dihydroxy-, oxide, trisodium salt |
foscarnet sodim |
MFCD00013973 |
trisodium dioxidophosphanecarboxylate oxide |
SODIUM FOSCARNET |
Phenytion Sodium |
Foscavir |
trisodium phosphonoformate |
FOSCARNET TRISODIUM SALT |
phosphonoformate sodium salt |