Lovastatin hydroxy acid sodium
Modify Date: 2024-01-02 23:15:19
Lovastatin hydroxy acid sodium structure
|
Common Name | Lovastatin hydroxy acid sodium | ||
|---|---|---|---|---|
| CAS Number | 75225-50-2 | Molecular Weight | 444.537 | |
| Density | N/A | Boiling Point | 602.3ºC at 760 mmHg | |
| Molecular Formula | C24H37NaO6 | Melting Point | 154-160ºC | |
| MSDS | N/A | Flash Point | 199.1ºC | |
Use of Lovastatin hydroxy acid sodiumLovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM[1]. |
| Name | Lovastatin sodium salt |
|---|---|
| Synonym | More Synonyms |
| Description | Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 0.6 nM (HMG-CoA reductase)[1] |
| In Vitro | Mevinolin in the hydroxy-acid form, mevinolinic acid, is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase [mevalonate: NADP+ oxidoreductase (CoA-acylating)][1]. |
| References |
| Boiling Point | 602.3ºC at 760 mmHg |
|---|---|
| Melting Point | 154-160ºC |
| Molecular Formula | C24H37NaO6 |
| Molecular Weight | 444.537 |
| Flash Point | 199.1ºC |
| Exact Mass | 444.248779 |
| PSA | 106.89000 |
| LogP | 2.38090 |
| Hazard Codes | Xi |
|---|
|
~%
Lovastatin hydr... CAS#:75225-50-2 |
| Literature: US2005/85528 A1, ; Page/Page column 4 ; US 20050085528 A1 |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
| MB 530B |
| sodium mevinolinate |
| lovastatin acid sodium salt |
| lovastatinic sodium salt |
| pravastatin |
| lovastatin hydroxy acid sodium salt |
| Sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthalenyl]-3,5-dihydroxyheptanoate |
| sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate |
| [1S-[1a(bS,dS),2a,6b,8b(R),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic acid monosodium salt |
| 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-8-[(2S)-2-methyl-1-oxobutoxy]-, sodium salt, (βR,δR,1S,2S,6R,8S,8aR)- (1:1) |
| lovastatin Na |
| Lovastatin Hydroxy Acid |
| LOVASTATIN SODIUM |
| mevinolin sodium salt |
| Lovastatin Impurity 2 |