N3-C5-NHS ester
Modify Date: 2024-01-13 19:32:51
N3-C5-NHS ester structure
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Common Name | N3-C5-NHS ester | ||
|---|---|---|---|---|
| CAS Number | 866363-70-4 | Molecular Weight | 254.24300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H14N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of N3-C5-NHS esterN3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Name | (2,5-dioxopyrrolidin-1-yl) 6-azidohexanoate |
|---|---|
| Synonym | More Synonyms |
| Description | N3-C5-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Noncleavable |
| References |
| Molecular Formula | C10H14N4O4 |
|---|---|
| Molecular Weight | 254.24300 |
| Exact Mass | 254.10200 |
| PSA | 113.43000 |
| LogP | 0.85496 |
|
~95%
N3-C5-NHS ester CAS#:866363-70-4 |
| Literature: Vasilyeva, Svetlana V.; Silnikov, Vladimir N.; Shatskaya, Natalia V.; Levina, Asya S.; Repkova, Marina N.; Zarytova, Valentina F. Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 3 p. 703 - 711 |
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~%
N3-C5-NHS ester CAS#:866363-70-4 |
| Literature: Grandjean, Cyrille; Boutonnier, Alain; Guerreiro, Catherine; Fournier, Jean-Michel; Mulard, Laurence A. Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7123 - 7132 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |
| 6-azidohexanoic acid N-hydroxysuccinimide ester |
| 6-azidohexanoic acid succinimidyl ester |
| 2,5-dioxopyrrolidin-1-yl 6-azidohexanoate |
| 2,5-Pyrrolidinedione,1-[(6-azido-1-oxohexyl)oxy] |
| N-(6-azidohexanoyl)succinimide |
| succinimidyl 6-azidohexanoate |