Hydroxy-PEG4-methylamine

Modify Date: 2024-01-31 10:34:55

Hydroxy-PEG4-methylamine Structure
Hydroxy-PEG4-methylamine structure
Common Name Hydroxy-PEG4-methylamine
CAS Number 90430-59-4 Molecular Weight 207.26700
Density N/A Boiling Point N/A
Molecular Formula C9H21NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG4-methylamine


Hydroxy-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethanol
Synonym More Synonyms

 Hydroxy-PEG4-methylamine Biological Activity

Description Hydroxy-PEG4-methylamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H21NO4
Molecular Weight 207.26700
Exact Mass 207.14700
PSA 59.95000

 Synonyms

5,8,11-Trioxa-2-azatridecan-13-ol