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美罗培南三水

美罗培南三水用途

Meropenem trihydrate是碳青霉烯抗生素,具有广谱 antibacterial 活性的。

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美罗培南三水名称

[ CAS 号 ]:
119478-56-7

[ 中文名 ]:
美洛培南

[ 英文名 ]:
Meropenem trihydrate

[中文别名 ]:

[英文别名 ]:

Meropenem trihydrate
MFCD00864966
Meropenem (trihydrate)

美罗培南三水生物活性

[ 描述 ]:

Meropenem trihydrate是碳青霉烯抗生素,具有广谱 antibacterial 活性的。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[参考文献]

[1]. Slaney, L., et al., In-vitro activity of meropenem against Neisseria gonorrhoeae, Haemophilus influenzae and H. ducreyi from Canada and Kenya. J Antimicrob Chemother, 1989. 24 Suppl A: p. 183-6.

[2]. Yang, Y.J. and D.M. Livermore, Interactions of meropenem with class I chromosomal beta-lactamases. J Antimicrob Chemother, 1989. 24 Suppl A: p. 207-17.

[3]. Makino, J., et al., [Pharmacokinetic study of penetration of meropenem into pleural effusion in patients with pleurisy]. Jpn J Antibiot, 2002. 55(1): p. 77-88.

[相关活性小分子]

美罗培南三水物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
627.4±55.0 °C at 760 mmHg

[ 分子式 ]:
C₁₇H₃₁N₃O₈S

[ 分子量 ]:
383.462

[ 闪点 ]:
333.2±31.5 °C

[ 精确质量 ]:
383.151489

[ PSA ]:
163.17000

[ LogP ]:
-2.59

[ 外观性状 ]:
白色至黄色固体

[ 蒸汽压 ]:
0.0±4.2 mmHg at 25°C

[ 折射率 ]:
1.639

[ 储存条件 ]:
?20°C

美罗培南三水MSDS

详细MSDS(安全技术说明书)

美罗培南三水安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933990090

美罗培南三水海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

美罗培南三水文献

Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.

PLoS Pathog. 11(2) , e1004645, (2015)

The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense strategies. We show that disruption of M. tuber...

Genetic acquisition of NDM gene offers sustainability among clinical isolates of Pseudomonas aeruginosa in clinical settings.

PLoS ONE 10(1) , e0116611, (2015)

New Delhi metallo β-lactamases are one of the most significant emerging resistance determinants towards carbapenem drugs. Their persistence and adaptability often depends on their genetic environment ...

Virulence attributes in Brazilian clinical isolates of Pseudomonas aeruginosa.

Int. J. Med. Microbiol. 304(8) , 990-1000, (2014)

Pseudomonas aeruginosa is an opportunistic human pathogen responsible for causing a huge variety of acute and chronic infections with significant levels of morbidity and mortality. Its success as a pa...

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