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芬迪烷盐酸盐

芬迪烷盐酸盐用途

Fendiline是非选择性的钙通道抑制剂。

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芬迪烷盐酸盐名称

[ CAS 号 ]:
13636-18-5

[ 中文名 ]:
芬迪烷盐酸盐

[ 英文名 ]:
Fendiline Hydrochloride

[中文别名 ]:

盐酸芬他林

[英文别名 ]:

Fendiline hydrochloride
Fendiline (hydrochloride)

芬迪烷盐酸盐生物活性

[ 描述 ]:

Fendiline是非选择性的钙通道抑制剂。

[ 相关类别 ]:

信号通路 >> 跨膜转运 >> 钙通道

研究领域 >> 心血管疾病

[相关活性小分子]

芬迪烷盐酸盐物理化学性质

[ 密度 ]:
1.031g/cm3

[ 沸点 ]:
452.1ºC at 760mmHg

[ 分子式 ]:
C₂₃H₂₆ClN

[ 分子量 ]:
351.91200

[ 闪点 ]:
207.9ºC

[ 精确质量 ]:
351.17500

[ PSA ]:
12.03000

[ LogP ]:
6.75230

[ 外观性状 ]:
粉末

[ 蒸汽压 ]:
2.3E-08mmHg at 25°C

[ 储存条件 ]:
-20℃

芬迪烷盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DP4790000

CHEMICAL NAME :: Benzylamine, N-(3,3-diphenylpropyl)-alpha-methyl-, hydrochloride

CAS REGISTRY NUMBER :: 13636-18-5

LAST UPDATED :: 199601

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C23-H25-N.Cl-H

MOLECULAR WEIGHT :: 351.95

WISWESSER LINE NOTATION :: 1YR&M2YR&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3262977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3262977

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芬迪烷盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
DP4790000

芬迪烷盐酸盐文献

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