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呋喃烯啶

呋喃烯啶用途

Furagin是nitrofurantoin的类似物,有抗菌活性。

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呋喃烯啶名称

[ CAS 号 ]:
1672-88-4

[ 中文名 ]:
呋喃烯啶

[ 英文名 ]:
Furagin

[中文别名 ]:

[英文别名 ]:

1-((3-(5-Nitro-2-furyl)allylidene)amino)-hydantoin
Furagin
MFCD00431319
Furazidin
Akritoin
Furazidine
NF 416

呋喃烯啶生物活性

[ 描述 ]:

Furagin是nitrofurantoin的类似物,有抗菌活性。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[参考文献]

[1]. Mannisto P, et al. Pharmacokinetics of furagin, a new nitrofurantoin congener, on human volunteers. Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):264-70.

[2]. Slapsyte G, et al. Cytogenetic analysis of children under long-term antibacterial therapy with nitroheterocyclic compound furagin. Mutat Res. 2001 Apr 5;491(1-2):25-30.

[3]. Dybowski B, et al. Ciprofloxacin and furagin in acute cystitis: comparison of early immune and microbiological results. Int J Antimicrob Agents. 2008 Feb;31(2):130-4.

[相关活性小分子]

呋喃烯啶物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 熔点 ]:
267-270ºC (dec.)

[ 分子式 ]:
C₁₀H₈N₄O₅

[ 分子量 ]:
264.194

[ 精确质量 ]:
264.049469

[ PSA ]:
120.73000

[ LogP ]:
0.81

[ 外观性状 ]:
粉末

[ 折射率 ]:
1.689

[ 储存条件 ]:
Refrigerator

呋喃烯啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MU3870000

CHEMICAL NAME :: Hydantoin, 1-((3-(5-nitro-2-furyl)allylidene)amino)-

CAS REGISTRY NUMBER :: 1672-88-4

BEILSTEIN REFERENCE NO. :: 0307076

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H8-N4-O5

MOLECULAR WEIGHT :: 264.22

WISWESSER LINE NOTATION :: T5OJ BNW E1U2UN- AT5NVMV EHJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Phage inhibition capacity

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 3 mg/L

REFERENCE :: CJMIAZ Canadian Journal of Microbiology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.1- 1954- Volume(issue)/page/year: 10,932,1964

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呋喃烯啶安全信息

[ 海关编码 ]:
2934999090

呋喃烯啶合成路线

详细合成路线

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呋喃烯啶海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%