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羧苄西林

羧苄西林用途

Carbenicillin是广谱的半合成青霉素衍生物。

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羧苄西林名称

[ CAS 号 ]:
4697-36-3

[ 中文名 ]:
羧苄西林

[ 英文名 ]:
Carbenicillin

[中文别名 ]:

[英文别名 ]:

Carboxybenzylpenicillin
CBPC
Carbenicilline
Geopen
Carbenicilina
Pyopen
Carboxybenzylpenicillin acid
Carbenicillinum

羧苄西林生物活性

[ 描述 ]:

Carbenicillin是广谱的半合成青霉素衍生物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[参考文献]

[1]. Moller, N.E., et al., Allergological examination of cystic fibrosis patients with skin reactions during carbenicillin treatment. Allergy, 1980. 35(2): p. 135-8.

[2]. Silva, J.d. and S. Fukai, The impact of carbenicillin, cefotaxime and vancomycin on chrysanthemum and tobacco TCL morphogenesis and Agrobacterium growth. J. Appl. Hort, 2001. 3(1): p. 3-12.

[相关活性小分子]

羧苄西林物理化学性质

[ 密度 ]:
1.53g/cm3

[ 沸点 ]:
737.8ºC at 760mmHg

[ 分子式 ]:
C₁₇H₁₈N₂O₆S

[ 分子量 ]:
378.40000

[ 闪点 ]:
400ºC

[ 精确质量 ]:
378.08900

[ PSA ]:
149.31000

[ LogP ]:
0.81530

[ 外观性状 ]:
淡黄色粉末

[ 折射率 ]:
1.675

[ 储存条件 ]:
−20°C

羧苄西林毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ON9104700

CHEMICAL NAME :: Malonamic acid, N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3 .2.0)hept-6-yl)-2- phenyl-

CAS REGISTRY NUMBER :: 4697-36-3

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C17-H18-N2-O6-S

MOLECULAR WEIGHT :: 378.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2363 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 280 mg/L

REFERENCE :: HUTODJ Human Toxicology. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants., RG 21 2XS, UK) V.1- 1981- Volume(issue)/page/year: 3,173,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3591 No. of Facilities: 178 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 10079 (estimated) No. of Female Employees: 8399 (estimated)

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羧苄西林安全信息

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R10

[ 安全声明 (欧洲) ]:
36/37

[ 危险品运输编码 ]:
UN 1170 3/PG 3

[ WGK德国 ]:
2