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十六烷基氯化吡啶

十六烷基氯化吡啶用途

氯化十六烷吡啶单水合物是一种阳离子季铵化合物, 用于某些类型的漱口水, 牙膏, 咽喉和鼻腔喷雾剂中, 是一种能杀死细菌和其他微生物的防腐剂, 可有效预防牙斑和减少牙龈炎。

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十六烷基氯化吡啶名称

[ CAS 号 ]:
6004-24-6

[ 中文名 ]:
十六烷基氯化吡啶

[ 英文名 ]:
Cetylpyridinium chloride monohydrate

[中文别名 ]:

[英文别名 ]:

Cetylpyridinum chloride
Cetylpyridinium chloride monohydrate
CETYLPYRIDINII CHLORIDUM
MFCD00149977
CPC MONOHYDRATE
EINECS 204-593-9
cetylpyridinium chloride
Chlorohexadecyl pyridine
Ceetylpyridiniumchloride
1-Hexadecylpyridin-1-ium chloride hydrate

十六烷基氯化吡啶生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[相关活性小分子]

十六烷基氯化吡啶物理化学性质

[ 熔点 ]:
81-84 °C

[ 分子式 ]:
C₂₁H₄₀ClNO

[ 分子量 ]:
358.001

[ 精确质量 ]:
357.279846

[ PSA ]:
13.11000

[ LogP ]:
3.39510

[ 外观性状 ]:
白色至淡米色粉末

[ 储存条件 ]:
库房低温通风干燥,与食品原料分开存放

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides.

十六烷基氯化吡啶MSDS

详细MSDS(安全技术说明书)

十六烷基氯化吡啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU5075000

CHEMICAL NAME :: Pyridinium, 1-hexadecyl-, chloride, monohydrate

CAS REGISTRY NUMBER :: 6004-24-6

LAST UPDATED :: 199603

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C21-H38-N.Cl.H2-O

MOLECULAR WEIGHT :: 358.07

WISWESSER LINE NOTATION :: T6KJ A16 &G &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,401,1942

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十六烷基氯化吡啶安全信息

[ 符号 ]:

GHS06, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H315-H319-H330-H335-H410

[ 警示性声明 ]:
P260-P304 + P340 + P310-P305 + P351 + P338-P403 + P233

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+:Verytoxic;

[ 风险声明 (欧洲) ]:
R25;R26;R38

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S7/9-S61-S26

[ 危险品运输编码 ]:
UN 2811 6.1/PG 1

[ WGK德国 ]:
3

[ RTECS号 ]:
UU5075000

[ 包装等级 ]:
I

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933399090

十六烷基氯化吡啶制备

将氯代十六烷和干吡啶油浴加热反应，再加入丙酮，混合物水浴加热溶解后再冷却得到产品。

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十六烷基氯化吡啶海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

十六烷基氯化吡啶文献

Exosomes: novel effectors of human platelet lysate activity.

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Despite the popularity of platelet-rich plasma (PRP) and platelet lysate (PL) in orthopaedic practice, the mechanism of action and the effectiveness of these therapeutic tools are still controversial....

Impact of lipid dynamic behavior on physical stability, in vitro release and skin permeation of genistein-loaded lipid nanoparticles.

Eur. J. Pharm. Biopharm. 88(1) , 40-7, (2014)

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Effect of silver nanoparticles on human mesenchymal stem cell differentiation.

Beilstein J. Nanotechnol. 5 , 2058-69, (2014)

Silver nanoparticles (Ag-NP) are one of the fastest growing products in nano-medicine due to their enhanced antibacterial activity at the nanoscale level. In biomedicine, hundreds of products have bee...

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十六烷基氯化吡啶

十六烷基氯化吡啶用途

十六烷基氯化吡啶名称

十六烷基氯化吡啶生物活性

十六烷基氯化吡啶物理化学性质

十六烷基氯化吡啶MSDS

详细MSDS(安全技术说明书)

十六烷基氯化吡啶毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

十六烷基氯化吡啶安全信息

十六烷基氯化吡啶制备

十六烷基氯化吡啶海关

十六烷基氯化吡啶文献

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