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β-羟基异戊酸

β-羟基异戊酸用途

3-Hydroxyisovaleric acid是尿液中排泄的正常人体代谢物。

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β-羟基异戊酸名称

[ CAS 号 ]:
625-08-1

[ 中文名 ]:
β-羟基异戊酸

[ 英文名 ]:
3-Hydroxyisovaleric acid

[中文别名 ]:

[英文别名 ]:

MFCD00059081
Beta-Hydroxyisovaleric Acid
3-hydroxy-3-methylbutanoic acid

β-羟基异戊酸生物活性

[ 描述 ]:

3-Hydroxyisovaleric acid是尿液中排泄的正常人体代谢物。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Mock NI, et al. Increased urinary excretion of 3-hydroxyisovaleric acid and decreased urinary excretion of biotin are sensitive early indicators of decreased biotin status in experimental biotin deficiency. 1997 Apr;65(4):951-8.

[相关活性小分子]

β-羟基异戊酸物理化学性质

[ 密度 ]:
0.938 g/mL at 25 °C(lit.)

[ 沸点 ]:
88 °C1 mm Hg(lit.)

[ 熔点 ]:
−80 °C(lit.)

[ 分子式 ]:
C₅H₁₀O₃

[ 分子量 ]:
118.13100

[ 闪点 ]:
113 °C

[ 精确质量 ]:
118.06300

[ PSA ]:
57.53000

[ LogP ]:
0.23200

[ 外观性状 ]:
无色至淡黄色液体

[ 折射率 ]:
n20/D 1.4415(lit.)

[ 储存条件 ]:
Refrigerator

β-羟基异戊酸MSDS

β-羟基异戊酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
UN 3334

[ WGK德国 ]:
3

[ 海关编码 ]:
2918199090

β-羟基异戊酸合成路线

β-羟基异戊酸上下游产品

β-羟基异戊酸上游产品

β-羟基异戊酸下游产品

β-羟基异戊酸制备

1. 烟草：BU，26。

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β-羟基异戊酸海关

[ 海关编码 ]: 2918199090

[ 中文概述 ]:
HS: 2918199090. 其他含醇基但不含其他含氧基羧酸（包括其酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

β-羟基异戊酸文献

Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.

J. Nutr. 144(12) , 1977-84, (2014)

Biotin functions as a cofactor for several carboxylase enzymes with key roles in metabolism. At present, the dietary requirement for biotin is unknown and intake recommendations are provided as Adequa...

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

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