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硫酸原黄素

硫酸原黄素用途

Proflavine硫酸盐是Acridine衍生物,抗细菌化合物。

硫酸原黄素名称

[ CAS 号 ]:
1811-28-5

[ 中文名 ]:
硫酸原黄素

[ 英文名 ]:
Proflavine (hemisulfate)

[中文别名 ]:

[英文别名 ]:

MFCD00149650
PROFLAVINE HEMISULPHATE
proflavine sulphate
PROFLAVINE SULFATE
3,6-Diaminoacridinium Monohydrogen Sulfate Hydrate
proflavin hemisulfate
Proflavine hemisulfate salt hydrate
Proflavine Hemisulfate
2 8-DIAMINOACRIDINE SULFATE
EINECS 217-320-3

硫酸原黄素生物活性

[ 描述 ]:

Proflavine硫酸盐是Acridine衍生物,抗细菌化合物。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

[相关活性小分子]

硫酸原黄素物理化学性质

[ 密度 ]:
1.346 g/cm3

[ 沸点 ]:
506.9ºC at 760 mmHg

[ 熔点 ]:
284-286ºC

[ 分子式 ]:
C₁₃H₁₁N_3.1/₂H₂O₄S

[ 分子量 ]:
258.29

[ 闪点 ]:
292.9ºC

[ PSA ]:
64.93000

[ LogP ]:
3.71480

[ 外观性状 ]:
橙色至红色粉末

[ 蒸汽压 ]:
0mmHg at 25°C

[ 储存条件 ]:
室温

硫酸原黄素MSDS

详细MSDS(安全技术说明书)

硫酸原黄素毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR9065100

CAS REGISTRY NUMBER :: 1811-28-5

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C13-H11-N3.1/2H2-O4-S

MOLECULAR WEIGHT :: 258.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 15 umol/L

REFERENCE :: JMOBAK Journal of Molecular Biology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 13,138,1965 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,195,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

硫酸原黄素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
AR9065100

[ 海关编码 ]:
2933990090

硫酸原黄素合成路线

详细合成路线

硫酸原黄素海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%