Metallo-β-lactamase-IN-2

Modify Date: 2024-04-07 19:10:24

Metallo-β-lactamase-IN-2 Structure
Metallo-β-lactamase-IN-2 structure
Common Name Metallo-β-lactamase-IN-2
CAS Number 1501705-61-8 Molecular Weight 250.14
Density N/A Boiling Point N/A
Molecular Formula C9H9Cl2NOS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Metallo-β-lactamase-IN-2


Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.1 μM (VIM-1), 1.3 μM (NDM-1), and 5.0 μM (IMP-7), respectively[1].

 Names

Name Metallo-β-lactamase-IN-2

 Metallo-β-lactamase-IN-2 Biological Activity

Description Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.1 μM (VIM-1), 1.3 μM (NDM-1), and 5.0 μM (IMP-7), respectively[1].
Related Catalog
Target

IC50: 0.1 ± 0.0 μM (VIM-1), 1.3 ± 0.0 μM (NDM-1), 5.0 ± 0.6 μM (IMP-7)[1]

References

[1]. Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922.

 Chemical & Physical Properties

Molecular Formula C9H9Cl2NOS
Molecular Weight 250.14