Aminooxy-PEG4-alcohol
Modify Date: 2024-01-16 09:14:03
Aminooxy-PEG4-alcohol structure
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Common Name | Aminooxy-PEG4-alcohol | ||
|---|---|---|---|---|
| CAS Number | 106492-60-8 | Molecular Weight | 209.24000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H19NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Aminooxy-PEG4-alcoholAminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
| Name | 2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethanol |
|---|
| Description | Aminooxy-PEG4-alcohol is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG4-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. |
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| Related Catalog | |
| Target |
PEGs Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
| References |
| Molecular Formula | C8H19NO5 |
|---|---|
| Molecular Weight | 209.24000 |
| Exact Mass | 209.12600 |
| PSA | 83.17000 |
| Storage condition | 2-8°C |