Azido-PEG2-VHL

Modify Date: 2024-03-01 13:47:55

Azido-PEG2-VHL Structure
Azido-PEG2-VHL structure
Common Name Azido-PEG2-VHL
CAS Number 2597167-22-9 Molecular Weight 615.74
Density N/A Boiling Point N/A
Molecular Formula C29H41N7O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-VHL


Azido-PEG2-VHL is a multikinase degrader which can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG2-VHL

 Azido-PEG2-VHL Biological Activity

Description Azido-PEG2-VHL is a multikinase degrader which can be used in the synthesis of PROTACs[1].
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
References

[1]. STATSYUK A, et, al. Multikinase degraders. WO2021021797A1.

[2]. Chung CW, et, al. Structural Insights into PROTAC-Mediated Degradation of Bcl-xL. ACS Chem Biol. 2020 Sep 18;15(9):2316-2323.

 Chemical & Physical Properties

Molecular Formula C29H41N7O6S
Molecular Weight 615.74