Curcumin D6

Modify Date: 2025-08-25 05:12:48

Curcumin D6 structure	Common Name	Curcumin D6
	CAS Number	1246833-26-0	Molecular Weight	374.41700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₄D₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Curcumin D6

Curcumin D6 (Diferuloylmethane D6) is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.

Name	(1E,6E)-1,7-bis[4-hydroxy-3-(trideuteriomethoxy)phenyl]hepta-1,6-diene-3,5-dione
Synonym	More Synonyms

Description	Curcumin D6 (Diferuloylmethane D6) is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Infection Signaling Pathways >> Apoptosis >> Ferroptosis Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology Signaling Pathways >> Autophagy >> Mitophagy Research Areas >> Metabolic Disease Signaling Pathways >> Epigenetics >> Histone Acetyltransferase Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
References	[1]. Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004. [2]. Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53. [3]. Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4. [4]. Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4. [5]. Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> Influenza Virus

Signaling Pathways >> NF-κB >> Keap1-Nrf2

Research Areas >> Infection

Signaling Pathways >> Apoptosis >> Ferroptosis

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Autophagy >> Mitophagy

Research Areas >> Metabolic Disease

Signaling Pathways >> Epigenetics >> Histone Acetyltransferase

Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain

References

[1]. Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004.

[2]. Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53.

[3]. Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4.

[4]. Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4.

[5]. Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303.

Molecular Formula	C₂₁H₁₄D₆O₆
Molecular Weight	374.41700
Exact Mass	374.16400
PSA	93.06000
LogP	3.36990

Hazard Codes	Xi

Halad-d6

Haidr-d6

Diferuloylmethane-d6

Curcumine-d6

Curcuma-d6

Ukon-d6

Haldar-d6

Curcumin-d6

C Yellow 15-d6

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Curcumin D6

Use of Curcumin D6

Names

Curcumin D6 Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.