m-PEG8-succinimidyl carbonate

Modify Date: 2024-01-09 18:45:48

m-PEG8-succinimidyl carbonate Structure
m-PEG8-succinimidyl carbonate structure
Common Name m-PEG8-succinimidyl carbonate
CAS Number 1372860-04-2 Molecular Weight 525.54
Density N/A Boiling Point N/A
Molecular Formula C22H39NO13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG8-succinimidyl carbonate


m-PEG8-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG8-succinimidyl carbonate
Synonym More Synonyms

 m-PEG8-succinimidyl carbonate Biological Activity

Description m-PEG8-succinimidyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H39NO13
Molecular Weight 525.54

 Synonyms

MFCD31380405