Fluorescein-PEG5-NHS ester

Modify Date: 2024-01-10 16:33:52

Fluorescein-PEG5-NHS ester Structure
Fluorescein-PEG5-NHS ester structure
Common Name Fluorescein-PEG5-NHS ester
CAS Number 2353409-62-6 Molecular Weight 795.81
Density N/A Boiling Point N/A
Molecular Formula C38H41N3O14S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fluorescein-PEG5-NHS ester


Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fluorescein-PEG5-NHS ester

 Fluorescein-PEG5-NHS ester Biological Activity

Description Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C38H41N3O14S
Molecular Weight 795.81