Fluorescein-PEG5-NHS ester

Modify Date: 2024-01-10 16:33:52

Fluorescein-PEG5-NHS ester structure	Common Name	Fluorescein-PEG5-NHS ester
	CAS Number	2353409-62-6	Molecular Weight	795.81
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₈H₄₁N₃O₁₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fluorescein-PEG5-NHS ester

Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Fluorescein-PEG5-NHS ester

Description	Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₈H₄₁N₃O₁₄S
Molecular Weight	795.81