Azido-PEG2-C2-sulfonic acid

Modify Date: 2024-01-10 16:14:14

Azido-PEG2-C2-sulfonic acid Structure
Azido-PEG2-C2-sulfonic acid structure
Common Name Azido-PEG2-C2-sulfonic acid
CAS Number 1817735-39-9 Molecular Weight 239.249
Density N/A Boiling Point N/A
Molecular Formula C6H13N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG2-C2-sulfonic acid


Azido-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG2-sulfonic acid
Synonym More Synonyms

 Azido-PEG2-C2-sulfonic acid Biological Activity

Description Azido-PEG2-C2-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C6H13N3O5S
Molecular Weight 239.249
Exact Mass 239.057587
LogP -1.95

 Synonyms

AZIDO-PEG2-SULFONIC ACID
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