PF-06700841

Modify Date: 2024-01-18 20:08:24

PF-06700841 structure	Common Name	PF-06700841
	CAS Number	1883299-62-4	Molecular Weight	389.40
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₁F₂N₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PF-06700841

PF-06700841 is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity[1].

Name	PF-06700841

Description	PF-06700841 is a dual JAK1 and TYK2 inhibitor with IC50s of 17 and 23 nM, respectively. Anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	IC50: 17 nM (JAK1), 23 nM (TYK2)[1]
References	[1]. Fensome A, et al. Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841). J Med Chem. 2018 Oct 11;61(19):8597-8612.

Molecular Formula	C₁₈H₂₁F₂N₇O
Molecular Weight	389.40
Storage condition	2-8℃

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PF-06700841 free base
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: PF-06700841 free base
Price: $850.0/100mg $1500.0/250mg $3200.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: PF-06700841 free base
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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