IACS-4619
Modify Date: 2024-09-10 17:55:48
IACS-4619 structure
|
Common Name | IACS-4619 | ||
|---|---|---|---|---|
| CAS Number | 1884209-98-6 | Molecular Weight | 195.266 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C10H17N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IACS-4619IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM; shows no off-target kinase activity in a panel of 97 kinases; exhibits excellent cell permeability and good metabolic stability in microsomes; an excellent tool for interrogation of the utility of MTH1 inhibition in the context of oncology. |
| Name | IACS-4619 |
|---|
| Description | IACS-4759 potent, selective aminopyrimidine MTH1 (MutT homolog 1) inhibitor with IC50 of 0.2 nM; shows no off-target kinase activity in a panel of 97 kinases; exhibits excellent cell permeability and good metabolic stability in microsomes; an excellent tool for interrogation of the utility of MTH1 inhibition in the context of oncology. |
|---|---|
| References | References 1. Petrocchi A, et al. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1503-7. View Related Products by Target DNA Repair Protein |
| Molecular Formula | C10H17N3O |
|---|---|
| Molecular Weight | 195.266 |