MELK inhibitor 17

Modify Date: 2024-01-04 18:07:09

MELK inhibitor 17 Structure
MELK inhibitor 17 structure
Common Name MELK inhibitor 17
CAS Number 2095596-44-2 Molecular Weight 539.62
Density N/A Boiling Point N/A
Molecular Formula C31H33N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MELK inhibitor 17


MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively.

 Names

Name MELK-IN-1

 MELK inhibitor 17 Biological Activity

Description MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively.
Related Catalog
Target

IC50: 3 nM (MELK) Ki: 0.39 nM (MELK)[1]

References

[1]. Edupuganti R, et al. Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. Bioorg Med Chem. 2017 May 1;25(9):2609-2616.

 Chemical & Physical Properties

Molecular Formula C31H33N5O4
Molecular Weight 539.62
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