VPC-13566

Modify Date: 2024-04-01 20:46:21

VPC-13566 Structure
VPC-13566 structure
Common Name VPC-13566
CAS Number 218464-59-6 Molecular Weight 258.32
Density N/A Boiling Point N/A
Molecular Formula C18H14N2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VPC-13566


VPC-13566 is an advanced BF3-specific small molecule that was previously reported to effectively inhibit AR transcriptional activity and to displace the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines, including an enzalutamide-resistant cell line, and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.

 Names

Name VPC-13566

 VPC-13566 Biological Activity

Description VPC-13566 is an advanced BF3-specific small molecule that was previously reported to effectively inhibit AR transcriptional activity and to displace the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines, including an enzalutamide-resistant cell line, and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.

 Chemical & Physical Properties

Molecular Formula C18H14N2
Molecular Weight 258.32
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