VPC-13789

Modify Date: 2024-04-01 18:07:51

VPC-13789 structure	Common Name	VPC-13789
	CAS Number	2761146-51-2	Molecular Weight	383.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₆F₃N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of VPC-13789

VPC-13789 is a potent, selective, and orally bioavailable antiandrogen. VPC-13789 can be used for the research of castration-resistant prostate cancer (CRPC) therapeutics. VPC-13789 inhibits androgen receptor (AR) transcriptional activity in LNCaP cells (IC50=0.19 μM)[1].

Name	VPC-13789

Description	VPC-13789 is a potent, selective, and orally bioavailable antiandrogen. VPC-13789 can be used for the research of castration-resistant prostate cancer (CRPC) therapeutics. VPC-13789 inhibits androgen receptor (AR) transcriptional activity in LNCaP cells (IC50=0.19 μM)[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Endocrinology Signaling Pathways >> Others >> Androgen Receptor
References	[1]. Eric Leblanc , et al. Development of 2-(5,6,7-Trifluoro-1 H-Indol-3-yl)-quinoline-5-carboxamide as a Potent, Selective, and Orally Available Inhibitor of Human Androgen Receptor Targeting Its Binding Function-3 for the Treatment of Castration-Resistant Prostate Cancer. J Med Chem. 2021 Oct 28;64(20):14968-14982.

Molecular Formula	C₂₁H₁₆F₃N₃O
Molecular Weight	383.37

VPC-13789

Use of VPC-13789

Names

VPC-13789 Biological Activity

Chemical & Physical Properties