CXCR2 antagonist 3
Modify Date: 2025-08-21 22:45:46
CXCR2 antagonist 3 structure
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Common Name | CXCR2 antagonist 3 | ||
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| CAS Number | 2647464-92-2 | Molecular Weight | 362.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H15FN2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CXCR2 antagonist 3CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3+ T lymphocytes into the Pan02 tumor tissues[1]. |
| Name | CXCR2 antagonist 3 |
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| Description | CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3+ T lymphocytes into the Pan02 tumor tissues[1]. |
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| Molecular Formula | C17H15FN2O4S |
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| Molecular Weight | 362.38 |
| InChIKey | HOMDQIYPTGGKMN-UHFFFAOYSA-N |
| SMILES | Cc1c(F)cccc1NC(=O)Nc1ccc2c(c1O)S(=O)(=O)CC=C2 |