CXCR2 antagonist 3

Modify Date: 2024-01-13 18:31:52

CXCR2 antagonist 3 structure	Common Name	CXCR2 antagonist 3
	CAS Number	2647464-92-2	Molecular Weight	362.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₅FN₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CXCR2 antagonist 3

CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3+ T lymphocytes into the Pan02 tumor tissues[1].

Name	CXCR2 antagonist 3

Description	CXCR2 antagonist 3 (compound 11h) is a potent antagonist of CXC chemokine receptor 2 (CXCR2). CXCR2 antagonist 3 demonstrates double-digit nanomolar potencies against CXCR2 and significantly inhibited neutrophil infiltration into the air pouch. CXCR2 antagonist 3 reduces the infiltration of neutrophils and MDSCs and enhance the infiltration of CD3+ T lymphocytes into the Pan02 tumor tissues[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> CXCR Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> CXCR
References	[1]. Dong Y, et al. Discovery of Benzocyclic Sulfone Derivatives as Potent CXCR2 Antagonists for Cancer Immunotherapy. J Med Chem. 2021;64(22):16626-16640.

Molecular Formula	C₁₇H₁₅FN₂O₄S
Molecular Weight	362.38

DC Chemicals Limited
China
Product Name: CXCR2 antagonist 3
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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