Androgen receptor antagonist 4

Modify Date: 2024-01-09 12:25:46

Androgen receptor antagonist 4 structure	Common Name	Androgen receptor antagonist 4
	CAS Number	354815-43-3	Molecular Weight	331.84
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₈ClN	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Androgen receptor antagonist 4

Androgen receptor antagonist 4 (Compound AT2) is an androgen receptor (AR) antagonist with an IC50 of 0.15 μM. Androgen receptor antagonist 4 efficiently antagonizes AR transcriptional activity, suppresses downstream target gene of AR, and blocks the DHT-induced AR nuclear translocation. Androgen receptor antagonist 4 shows anticancer activities[1].

Name	Androgen receptor antagonist 4

Description	Androgen receptor antagonist 4 (Compound AT2) is an androgen receptor (AR) antagonist with an IC50 of 0.15 μM. Androgen receptor antagonist 4 efficiently antagonizes AR transcriptional activity, suppresses downstream target gene of AR, and blocks the DHT-induced AR nuclear translocation. Androgen receptor antagonist 4 shows anticancer activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Androgen Receptor
Target	IC50: 0.15 μM (Androgen receptor)[1]
References	[1]. Tang Q, et al. Novel androgen receptor antagonist identified by structure-based virtual screening, structural optimization, and biological evaluation. Eur J Med Chem. 2020 Apr 15;192:112156.

Molecular Formula	C₂₂H₁₈ClN
Molecular Weight	331.84

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Androgen receptor antagonist 4

Use of Androgen receptor antagonist 4

Names

Androgen receptor antagonist 4 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.