Ph-PEG3 structure
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Common Name | Ph-PEG3 | ||
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CAS Number | 7204-16-2 | Molecular Weight | 226.26900 | |
Density | 1.097g/cm3 | Boiling Point | 351.9ºC at 760 mmHg | |
Molecular Formula | C12H18O4 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 166.6ºC |
Use of Ph-PEG3Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | 2-[2-(2-phenoxyethoxy)ethoxy]ethanol |
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Synonym | More Synonyms |
Description | Ph-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.097g/cm3 |
---|---|
Boiling Point | 351.9ºC at 760 mmHg |
Molecular Formula | C12H18O4 |
Molecular Weight | 226.26900 |
Flash Point | 166.6ºC |
Exact Mass | 226.12100 |
PSA | 47.92000 |
LogP | 1.09090 |
Index of Refraction | 1.504 |
~71% Ph-PEG3 CAS#:7204-16-2 |
Literature: Kimura, Masaru; Kajita, Kazushige; Onoda, Naoyuki; Morosawa, Shiro Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4887 - 4892 |
~65% Ph-PEG3 CAS#:7204-16-2 |
Literature: Jursic, Branko Tetrahedron, 1988 , vol. 44, # 5 p. 1553 - 1558 |
~%
Detail
|
Literature: DOW GLOBAL TECHNOLOGIES INC. Patent: WO2009/76275 A1, 2009 ; Location in patent: Page/Page column 13-15 ; |
~% Ph-PEG3 CAS#:7204-16-2 |
Literature: Mertens, Ingrid J. A.; Wegh, Rene; Jenneskens, Leonardus W.; Vlietstra, Edward J.; Van Der Kerk-van Hoof, Anca; Zwikker, Jan W.; Cleij, Thomas J.; Smeets, Wilberth J. J.; Veldman, Nora; Spek, Anthony L. Journal of the Chemical Society. Perkin Transactions 2, 1998 , # 3 p. 725 - 736 |
~% Ph-PEG3 CAS#:7204-16-2 |
Literature: Jursic, Branko Tetrahedron, 1988 , vol. 44, # 5 p. 1553 - 1558 |
~%
Detail
|
Literature: DOW GLOBAL TECHNOLOGIES INC. Patent: WO2009/76275 A1, 2009 ; Location in patent: Page/Page column 13-15 ; |
~% Ph-PEG3 CAS#:7204-16-2 |
Literature: Shukis; Tallman Journal of the American Chemical Society, 1944 , vol. 66, p. 1462 |
~% Ph-PEG3 CAS#:7204-16-2 |
Literature: Miller et al. Journal of the Chemical Society, 1950 , p. 3623,3628 |
~% Ph-PEG3 CAS#:7204-16-2 |
Literature: I.G. Farbenind. Patent: DE519730 , 1925 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 561 |
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[2-(2-Hydroxy-aethoxy)-aethyl]-(2-phenoxy-aethyl)-aether |
2-[2-(2-phenoxy-ethoxy)-ethoxy]-ethanol |
8-phenoxy-3,6-dioxa-1-octanol |
2-[2-(2-phenoxyethoxy)ethoxy]ethan-1-ol |
Ethanol,2-[2-(2-phenoxyethoxy)ethoxy] |
triethylene glycol phenyl ether |
2-[2-(2-Phenoxy-aethoxy)-aethoxy]-aethanol |
bis[2-(2-hydroxyethoxy)ethoxy]benzene |
TRIETHYLENE GLYCOL MONOPHENYL ETHER |