Curcumin D6

Curcumin D6用途

Curcumin D6 (Diferuloylmethane D6) 是Curcumin (Turmeric yellow) 的氘代标记物。Curcumin (Turmeric yellow) 是一种天然酚类化合物,具有抗炎,抗氧化,抗增殖和抗血管生成等多种活性。 Curcumin是p300组蛋白乙酰转移酶 (HATs) 抑制剂,也显示对 NF-κB 和MAPKs 的抑制作用。

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Curcumin D6名称

[ CAS 号 ]:
1246833-26-0

[ 中文名 ]:
姜黄素-d6

[ 英文名 ]:
Curcumin D6

[英文别名 ]:

Halad-d6
Haidr-d6
Diferuloylmethane-d6
Curcumine-d6
Curcuma-d6
Ukon-d6
Haldar-d6
Curcumin-d6
C Yellow 15-d6

Curcumin D6生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 抗感染 >> 流感病毒

信号通路 >> NF-κB信号通路 >> KEAP1-Nrf2

研究领域 >> 感染

信号通路 >> 细胞凋亡 >> Ferroptosis

信号通路 >> 自噬 >> 自噬

研究领域 >> 炎症/免疫

信号通路 >> 自噬 >> 自噬

研究领域 >> 代谢疾病

信号通路 >> 表观遗传学 >> 组蛋白乙酰转移酶

信号通路 >> 表观遗传学 >> 表观遗传读者域

[参考文献]

[1]. Gao S, et al. Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion. Food Chem Toxicol. 2013 Jul 18. pii: S0278-6915(13)004.

[2]. Nasiri M, et al. Curcumin and Silibinin Inhibit Telomerase Expression in T47D Human Breast Cancer Cells. Asian Pac J Cancer Prev. 2013;14(6):3449-53.

[3]. Jiang H, et al. Antidepressant-like effects of curcumin in chronic mild stress of rats: Involvement of its anti-inflammatory action. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jul 20. pii: S0278-5846(13)00150-4.

[4]. Guo H, et al. Curcumin induces cell cycle arrest and apoptosis of prostate cancer cells by regulating the expression of IkappaBalpha, c-Jun and androgen receptor. Pharmazie. 2013 Jun;68(6):431-4.

[5]. Zhu X, et al. Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model. PLoS One. 2014 Mar 6;9(3):e91303.

Curcumin D6物理化学性质

[ 分子式 ]:
C₂₁H₁₄D₆O₆

[ 分子量 ]:
374.41700

[ 精确质量 ]:
374.16400

[ PSA ]:
93.06000

[ LogP ]:
3.36990

[ 储存条件 ]:
2-8°C，干燥，密封

Curcumin D6安全信息

[ 危害码 (欧洲) ]:
Xi