< 生产厂家价格 >

那氟沙星

那氟沙星用途

【用途一】
一种喹诺酮类抗菌新药，抗菌谱广，对金黄色葡萄球菌、表皮葡萄球菌、化脓链球菌、大肠杆菌、铜绿假单胞菌等需氧菌和痤疮丙酸杆菌、脆弱拟杆菌等厌氧菌有很好的抗菌活性。其疗效比传统的抗菌药四环素、红霉素、氯洁霉素好。

点击显示

那氟沙星名称

[ CAS 号 ]:
124858-35-1

[ 中文名 ]:
那地沙星

[ 英文名 ]:
Nadifloxacin

[中文别名 ]:

[英文别名 ]:

Nadiflox
Activon
Acuatim
Jinofloxacin
Nadifloxacin
Nadixa
Nadoxin
MFCD00865081

那氟沙星生物活性

[ 描述 ]:

Nadifloxacin(OPC7251)是广谱的氟喹诺酮类抗生素,对寻常粉刺有效。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌

研究领域 >> 炎症/免疫

[参考文献]

[1]. Jacobs, M.R. and P.C. Appelbaum, Nadifloxacin: a quinolone for topical treatment of skin infections and potential for systemic use of its active isomer, WCK 771. Expert Opin Pharmacother, 2006. 7(14): p. 1957-66.

[2]. Choudhury, S., et al., Efficacy and safety of topical nadifloxacin and benzoyl peroxide versus clindamycin and benzoyl peroxide in acne vulgaris: A randomized controlled trial. Indian J Pharmacol, 2011. 43(6): p. 628-31.

[相关活性小分子]

那氟沙星物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
624.9±55.0 °C at 760 mmHg

[ 熔点 ]:
245-247ºC (dec)

[ 分子式 ]:
C₁₉H₂₁FN₂O₄

[ 分子量 ]:
360.379

[ 闪点 ]:
331.7±31.5 °C

[ 精确质量 ]:
360.148529

[ PSA ]:
82.77000

[ LogP ]:
1.95

[ 外观性状 ]:
灰白色结晶固体

[ 蒸汽压 ]:
0.0±1.9 mmHg at 25°C

[ 折射率 ]:
1.669

[ 储存条件 ]:
-20?C Freezer

那氟沙星MSDS

那氟沙星安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

那氟沙星合成路线

那氟沙星上下游产品

那氟沙星上游产品

那氟沙星下游产品

那氟沙星文献

Efficacy and safety of nadifloxacin for bacterial skin infections: results from clinical and post-marketing studies.

Dermatol. Ther. (Heidelb.) 4(2) , 233-48, (2014)

Skin and soft tissue infections involve microbial invasion of the skin and underlying soft tissues and are estimated to affect 7-10% of hospitalized patients worldwide. Nadifloxacin, a topical fluoroq...

Green Nail Syndrome (Pseudomonas aeruginosa Nail Infection): Two Cases Successfully Treated with Topical Nadifloxacin, an Acne Medication.

Case Rep. Dermatol. 6(2) , 180-4, (2014)

Green nail syndrome (GNS) caused by Pseudomonas aeruginosa is the most common bacterial nail infection. The treatment of GNS is challenging in many cases and recommendations based on clinical trials a...

Design and evaluation of microemulsion gel system of nadifloxacin.

Indian J. Pharm. Sci. 74(3) , 237-47, (2012)

Topical microemulsion systems for the antiacne agent, nadifloxacin were designed and developed to overcome the problems associated with the cutaneous delivery due to poor water solubility. The solubil...

更多文献

那氟沙星

那氟沙星用途

那氟沙星名称

那氟沙星生物活性

那氟沙星物理化学性质

那氟沙星MSDS

详细MSDS(安全技术说明书)

那氟沙星安全信息

那氟沙星合成路线

详细合成路线

那氟沙星上下游产品

那氟沙星上游产品

那氟沙星下游产品

那氟沙星文献

相关化工产品/化学物质：

相关药品：

推荐生产厂家/供应商：

相关化合物