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2-乙酰氨基-5-硝基噻唑

2-乙酰氨基-5-硝基噻唑用途

Nithiamide是非-5-硝基咪唑药物, 是一种兽用抗生素。
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2-乙酰氨基-5-硝基噻唑名称

[ CAS 号 ]:
140-40-9

[ 中文名 ]:
醋胺硝唑

[ 英文名 ]:
Nithiamide

[中文别名 ]:

[英文别名 ]:

2-乙酰氨基-5-硝基噻唑生物活性

[ 描述 ]:

Nithiamide是非-5-硝基咪唑药物, 是一种兽用抗生素。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 细菌
研究领域 >> 感染

[相关活性小分子]

嘌呤霉素二盐酸盐 | G-418 硫酸盐 | 衣霉素 | 潮霉素B | 盐霉素 | 阿维巴坦钠 | 硫酸新霉素 | 法硼巴坦 | 甲氧西林钠 | 利福平 | 甲硝唑 | 羧苄青霉素钠 | 头孢他啶 | 盐酸依拉环素 | 头孢噻肟钠

2-乙酰氨基-5-硝基噻唑物理化学性质

[ 密度 ]:
1.598g/cm3

[ 沸点 ]:
303.8ºC at 760mmHg

[ 熔点 ]:
263°C (dec.)

[ 分子式 ]:
C5H5N3O3S

[ 分子量 ]:
187.17600

[ 闪点 ]:
137.5ºC

[ 精确质量 ]:
187.00500

[ PSA ]:
116.05000

[ LogP ]:
1.60590

[ 外观性状 ]:
固体;White to Amber powder to crystal

[ 蒸汽压 ]:
0.000911mmHg at 25°C

[ 折射率 ]:
1.666

[ 储存条件 ]:
避免光

2-乙酰氨基-5-硝基噻唑MSDS

详细MSDS(安全技术说明书)

2-乙酰氨基-5-硝基噻唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ1570000
CHEMICAL NAME :
Thiazole, 2-acetamido-5-nitro-
CAS REGISTRY NUMBER :
140-40-9
BEILSTEIN REFERENCE NO. :
0167361
LAST UPDATED :
199612
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C5-H5-N3-O3-S
MOLECULAR WEIGHT :
187.19
WISWESSER LINE NOTATION :
T5N CSJ BMV1 DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Behavioral - food intake (animal) Blood - changes in cell count (unspecified) Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - turkey
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Gene conversion and mitotic recombination
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
DOSE/DURATION :
200 ppm
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 118,153,1983
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2-乙酰氨基-5-硝基噻唑安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S22-S36/37

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
XJ1570000

[ 海关编码 ]:
2934100090

2-乙酰氨基-5-硝基噻唑合成路线

详细合成路线

2-乙酰氨基-5-硝基噻唑上下游产品

2-乙酰氨基-5-硝基噻唑上游产品

2-乙酰氨基-5-硝基噻唑下游产品

2-乙酰氨基-5-硝基噻唑制备

由2-氨基噻唑为原料制得。

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2-乙酰氨基-5-硝基噻唑海关

[ 海关编码 ]: 2934100090

[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-乙酰氨基-5-硝基噻唑文献

Back to the future: oral targeted therapy for RA and other autoimmune diseases.

Nat. Rev. Rheumatol. 9(3) , 173-82, (2013)

The molecular biology revolution coupled with the development of monoclonal antibody technology enabled remarkable progress in rheumatology therapy, comprising an array of highly effective biologic ag...

[The treatment of intra-abdominal abscess].

Klin. Khir. (7) , 32-3, (1998)

The experience of treatment of 18 patients with intraabdominal abscess using the regional laparostomy conduction and introducing nitazol, immobilized on polymethylsiloxane, in the abscess cavity, was ...

[Nitazole--an antimicrobial substance].

Mikrobiol. Z. 60(1) , 83-91, (1998)

The antibacterial activity of protistocide drug nitazole has been revealed for the first time in the 80's at the Laboratory of Clinical Microbiology of the Mechnikov Research Institute of Microbiology...


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推荐生产厂家/供应商：

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐乾明

产品详情：醋胺硝唑

公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥518.0/1g ￥1868.0/5g

联系人：刘佳

产品详情：2-乙酰氨基-5-硝基噻唑

公司名：上海脉铂医药科技有限公司

区域：上海市嘉定区

价格：
￥389.0/50mg ￥639.0/1g ￥需询单/1g ￥需询单/1g

联系人：李先生

产品详情：Nithiamide

公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥101.0/1g ￥360.0/5g ￥392.0/50mg ￥需询单/1ml

联系人：夏言

产品详情：[Perfemiker]2-乙酰氨基-5-硝基噻唑,≥98%

公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥76.9/1g ￥960.9/25g ￥242.9/5g ￥2925.9/100g

联系人：阿拉丁

产品详情：2-乙酰氨基-5-硝基噻唑

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相关化合物

【2-乙酰氨基-5-硝基噻唑】化源网提供2-乙酰氨基-5-硝基噻唑CAS号140-40-9，2-乙酰氨基-5-硝基噻唑MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询2-乙酰氨基-5-硝基噻唑上化源网，专业又轻松。>>电脑版：2-乙酰氨基-5-硝基噻唑

标题：2-乙酰氨基-5-硝基噻唑_MSDS_用途_密度_CAS号【140-40-9】_化源网 地址：https://m.chemsrc.com/mip/cas/140-40-9_834449.html