Maropitant

Maropitant是神经激肽(NK1)受体拮抗剂。

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 神经激肽受体

信号通路 >> 神经信号通路 >> 神经激肽受体

研究领域 >> 神经疾病

[1]. Hay Kraus BL. Efficacy of maropitant in preventing vomiting in dogs premedicated with hydromorphone. Vet Anaesth Analg. 2013 Jan;40(1):28-34.

[2]. Lesman SP, Boucher JF, Grover GS, et al. The pharmacokinetics of maropitant citrate dosed orally to dogs at 2 mg/kg and 8 mg/kg once daily for 14 days consecutive days. J Vet Pharmacol Ther. 2012 Nov 20.

[3]. Alvillar BM, Boscan P, Mama KR, et al. Effect of epidural and intravenous use of the neurokinin-1 (NK-1) receptor antagonist maropitant on the sevoflurane minimum alveolar concentration (MAC) in dogs. Vet Anaesth Analg. 2012 Mar;39(2):201-5.

[4]. Ramsey DS, Kincaid K, Watkins JA et al. Safety and efficacy of injectable and oral maropitant, a selective neurokinin 1 receptor antagonist, in a randomized clinical trial for treatment of vomiting in dogs. J Vet Pharmacol Ther. 2008 Dec;31(6):538-43. doi: 10.1111/j.1365-2885.2008.00992.x.

[5]. Benchaoui HA, Cox SR, Schneider RP et al. The pharmacokinetics of maropitant, a novel neurokinin type-1 receptor antagonist, in dogs. J Vet Pharmacol Ther. 2007 Aug;30(4):336-44.

[6]. Maropitant

P物质 | 罗拉吡坦 | 3-甲基-2-苯基-N-((1S)-1-苯基丙基)喹啉-4-甲酰胺 | 非唑奈坦 | 奈妥匹坦 | 精氨酰-脯氨酰-赖氨酰-脯氨酰-谷氨酰-谷氨酰-苯丙氨酰-苯丙氨酰-SAR-亮氨酸-蛋氨酸[O2]-胺 | Pavinetant | 琥珀酰基-天冬氨酰-苯丙氨酰-(N-甲基)-苯丙氨酰-甘氨酰-亮氨酰-蛋氨酸胺 | (R)-(+)-2-氨基-4-羟基丁酸 | Serlopitant | 他奈坦 | Y1受体拮抗剂1 | [bAla8]-神经激肽A(4-10) | Befetupitant