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盐酸萘替芬

盐酸萘替芬用途

Naftifine盐酸盐是广谱的抗真菌化合物。

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盐酸萘替芬名称

[ CAS 号 ]:
65473-14-5

[ 中文名 ]:
盐酸萘替芬

[ 英文名 ]:
Naftifine hydrochloride

[中文别名 ]:

[英文别名 ]:

MFCD00059047
Naftifine HCl

盐酸萘替芬生物活性

[ 描述 ]:

Naftifine盐酸盐是广谱的抗真菌化合物。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 真菌

研究领域 >> 感染

[参考文献]

[1]. Georgopoulos, A., et al., In vitro activity of naftifine, a new antifungal agent. Antimicrob Agents Chemother, 1981. 19(3): p. 386-9.

[2]. Ryder, N.S., G. Seidl, and P.F. Troke, Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. Antimicrob Agents Chemother, 1984. 25(4): p. 483-7.

[3]. Parish, L.C., et al., A double-blind, randomized, vehicle-controlled study evaluating the efficacy and safety of naftifine 2% cream in tinea cruris. J Drugs Dermatol, 2011. 10(10): p. 1142-7.

[4]. Gupta, A.K., J.E. Ryder, and E.A. Cooper, Naftifine: a review. J Cutan Med Surg, 2008. 12(2): p. 51-8.

[相关活性小分子]

盐酸萘替芬物理化学性质

[ 沸点 ]:
440.1ºC at 760 mmHg

[ 熔点 ]:
172-175ºC

[ 分子式 ]:
C₂₁H₂₂ClN

[ 分子量 ]:
323.859

[ 闪点 ]:
194.4ºC

[ 精确质量 ]:
323.144073

[ PSA ]:
3.24000

[ LogP ]:
5.78700

[ 储存条件 ]:
-20?C Freezer

盐酸萘替芬MSDS

详细MSDS(安全技术说明书)

盐酸萘替芬安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2942000000

盐酸萘替芬海关

[ 海关编码 ]: 2942000000

盐酸萘替芬文献

DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.

Nucleic Acids Res. 39 , D1035-41., (2011)

DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, ...

Allergic contact dermatitis from naftifine in a child without cross-reaction to terbinafine.

J. Eur. Acad. Dermatol. Venereol. 11(1) , 72-3, (1998)

Allergic contact dermatitis from naftifine has been scarcely described in the English literature, all of them in adults. We report a case of a 12-year-old girl who developed an acute eczema on her nec...

RIPK3-mediated necroptosis regulates cardiac allograft rejection.

Journal. of. Drugs in. Dermatology. 10(11) , 1282-8, (2011)

Cell death results in tissue damage and ultimately donor graft rejection and can occur as an active molecular process through apoptotic, necrotic and newly identified receptor interacting protein 1 an...

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