乙氧基喹啉
乙氧基喹啉用途
乙氧基喹啉名称
[ CAS 号 ]:
91-53-2
[ 中文名 ]:
乙氧喹啉
[ 英文名 ]:
Ethoxyquin
[中文别名 ]:
- 乙氧喹
- 6-乙氧基-2,2,4-三甲基-1,2-二氢喹啉
- 乙氧基喹啉
- 6-乙氧基-1,2-二氢-2,2,4-三甲基喹啉
- 1,2-二氢-6-乙氧基-2,2,4-三甲基喹啉
- 6-乙氧基-2,2,4-三甲基-1,2-二氢化喹啉
[英文别名 ]:
- 6-Ethoxy-2,2,4-trimethyl-1,2-dihydroquinoline
- Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-
- EINECS 202-075-7
- 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinoline
- emq
- quinoled
- UNII-9T1410R4OR
- 2,2,4-trimethyl-6-ethoxy-1,2-dihydroquinoline
- nocracaw
- amea100
乙氧基喹啉生物活性
[ 描述 ]:
[ 相关类别 ]:
[ 靶点 ]
HSP90
[体外研究]
[体内研究]
[激酶实验]
[细胞实验]
[动物实验]
[参考文献]
[相关活性小分子]
乙氧基喹啉物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
333.1±42.0 °C at 760 mmHg
[ 熔点 ]:
<0ºC
[ 分子式 ]:
C14H19NO
[ 分子量 ]:
217.307
[ 闪点 ]:
137.8±17.3 °C
[ 精确质量 ]:
217.146667
[ PSA ]:
21.26000
[ LogP ]:
3.93
[ 外观性状 ]:
黄色至红色-棕色液体
[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C
[ 折射率 ]:
1.512
[ 储存条件 ]:
库房低温,通风,干燥,防火,与氧化剂,食品原料分开存放
[ 稳定性 ]:
Stable. Combustible. Incompatible with oxidizing agents, strong acids. Polymerizes if heated. May polymerize upon exposure to light and air.
[ 水溶解性 ]:
ethanol: 50 mL/L, clear, brown | <0.1 g/100 mL at 20 ºC
乙氧基喹啉MSDS
乙氧基喹啉毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VB8225000
- CHEMICAL NAME :
- Quinoline, 6-ethoxy-1,2-dihydro-2,2,4-trimethyl-
- CAS REGISTRY NUMBER :
- 91-53-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- C14-H19-N-O
- MOLECULAR WEIGHT :
- 217.34
- WISWESSER LINE NOTATION :
- T66 BM CHJ C1 C1 E1 HO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1730 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 178 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - coma
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14377 mg/kg/3W-C
- TOXIC EFFECTS :
- Blood - change in clotting factors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 63 gm/kg/30W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 122 gm/kg/58W-C
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12 gm/kg/29W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - changes in bladder weight
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 13 gm-kg/4W (Continuous)
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 99,37,1989 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83809 No. of Facilities: 204 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 3572 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83809 No. of Facilities: 876 (estimated) No. of Industries: 6 No. of Occupations: 14 No. of Employees: 7945 (estimated)
乙氧基喹啉安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302
[ 警示性声明 ]:
P301 + P312 + P330
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful
[ 风险声明 (欧洲) ]:
R22
[ 安全声明 (欧洲) ]:
S24
[ 危险品运输编码 ]:
NONH for all modes of transport
[ WGK德国 ]:
1
[ RTECS号 ]:
VB8225000
[ 海关编码 ]:
2933499090
乙氧基喹啉合成路线
乙氧基喹啉上下游产品
乙氧基喹啉上游产品
乙氧基喹啉下游产品
乙氧基喹啉制备
1.由对氨基苯乙醚与丙酮缩合而得。在苯磺酸催化下,对氨基苯乙醚与丙酮在155-165℃进行缩合反应。反应生成的水和未反应的丙酮反回丙酮蒸发器回收使用。缩合反应后,蒸馏得到成品。也可以用1%碘和催化剂,在120-130℃进行缩合反应。原料消耗(kg/t)对氨基苯乙醚 1000丙酮 800苯磺酸 100
每吨产品消耗对氨基苯乙醚1000kg、丙酮800kg、苯磺酸100kg。工艺流
程如下:
也可以用1%的碘、浓盐酸、三氯化铝、溴化氢等作催化剂,在100~170℃进行缩合反应制备乙氧喹。
2.一般由对氨基苯乙醚与丙酮在催化剂作用下缩合而得。
3.在苯磺酸催化下,对氨基苯乙醚与丙酮进行缩合反应制得。
乙氧基喹啉海关
[ 海关编码 ]: 2933499090
[ 中文概述 ]:
2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
乙氧基喹啉文献
Toxicol. Lett. 193(2) , 194-9, (2010)
N-tert-butyl-alpha-phenylnitrone (PBN) and its new derivative N-(Pyridine-4-ylmethylidene)-2-carboxy-tert-butylamine N-oxide (PBNC) were synthesized and used to modulate ethoxyquin (1,2-dihydro-6-etho...
Effects of a dietary antioxidant blend and vitamin E on fatty acid profile, liver function, and inflammatory response in broiler chickens fed a diet high in oxidants.Poult. Sci. 93(7) , 1658-66, (2014)
The aim of the current study was to determine the effects of a dietary antioxidant blend and vitamin E on fatty acid profile, inflammatory response, and liver function. Cobb 500 male broilers (n = 1,2...
Effects of a dietary antioxidant blend and vitamin E on growth performance, oxidative status, and meat quality in broiler chickens fed a diet high in oxidants.Poult. Sci. 93(7) , 1649-57, (2014)
The aim of the study was to determine the effects of a dietary antioxidant blend (AB) and vitamin E on performance, oxidative status, and meat quality. Cobb 500 male broilers (n = 1,200, d 0) were ran...
相关化工产品/化学物质:
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
产品详情:乙氧基喹啉
公司名:南通润丰石油化工有限公司
区域:南通市崇川区
价格:
¥需询单/1kg
¥需询单/1ton
联系人:曹经理
产品详情:乙氧基喹啉
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥175.0/100g
¥585.0/500g
联系人:刘佳
产品详情:乙氧基喹啉
公司名:上海源溪生物科技有限公司
区域:上海市浦东新区
价格:
¥需询单/1g
联系人:赖经理
产品详情:Amea 100
公司名:上海脉铂医药科技有限公司
区域:上海市嘉定区
价格:
¥389.0/10g
¥684.0/25g
¥1260.0/50g
¥需询单/50g
联系人:李先生
产品详情:Ethoxyquin
查看所有供应商请点击:
相关化合物
【乙氧基喹啉】化源网提供乙氧基喹啉CAS号91-53-2,乙氧基喹啉MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询乙氧基喹啉上化源网,专业又轻松。>>电脑版:乙氧基喹啉
标题:乙氧基喹啉_MSDS_用途_密度_乙氧基喹啉CAS号【91-53-2】_化源网 地址:https://m.chemsrc.com/mip/cas/91-53-2_895879.html