Biotin-PEG2-NH-Boc

Modify Date: 2024-01-08 11:56:15

Biotin-PEG2-NH-Boc Structure
Biotin-PEG2-NH-Boc structure
Common Name Biotin-PEG2-NH-Boc
CAS Number 175885-18-4 Molecular Weight 474.61
Density N/A Boiling Point N/A
Molecular Formula C21H38N4O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG2-NH-Boc


Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG2-NH-Boc
Synonym More Synonyms

 Biotin-PEG2-NH-Boc Biological Activity

Description Biotin-PEG2-NH-Boc is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

 Chemical & Physical Properties

Molecular Formula C21H38N4O6S
Molecular Weight 474.61

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD30527392