Tyk2-IN-9

Modify Date: 2024-01-14 10:20:20

Tyk2-IN-9 structure	Common Name	Tyk2-IN-9
	CAS Number	2127109-85-5	Molecular Weight	383.41
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₇N₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tyk2-IN-9

Tyk2-IN-9 is a potent,selective and specific inhibitor of JAK kinases, inhibits Tyk2, JAK1 and JAK2 with IC50 values of 6 nM, 21nM and 6nM, respectively. Tyk2-IN-9, example 19, is extracted from patent US2017240552A1[1].

Name	Tyk2-IN-9

Description	Tyk2-IN-9 is a potent,selective and specific inhibitor of JAK kinases, inhibits Tyk2, JAK1 and JAK2 with IC50 values of 6 nM, 21nM and 6nM, respectively. Tyk2-IN-9, example 19, is extracted from patent US2017240552A1[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	Tyk2:6 nM (IC50) JAK1:21 nM (IC50) JAK2:8 nM (IC50)
In Vitro	Tyk2-IN-9 has the ability to inhibit IL-12 signaling in a human whole blood with an IC50 value of 28 nM in a flow cytometry assay[1].
References	[1]. Matthew Frank Brown, et al. Pyrazolo[1,5-a]pyrazin-4-yl derivatives. Patent US20170240552A1

Molecular Formula	C₂₀H₁₇N₉
Molecular Weight	383.41

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tyk2-IN-9
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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