Tyk2-IN-8
Modify Date: 2024-01-09 20:15:07
Tyk2-IN-8 structure
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Common Name | Tyk2-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 2127109-84-4 | Molecular Weight | 383.41 | |
| Density | 1.46±0.1 g/cm3(Predicted) | Boiling Point | N/A | |
| Molecular Formula | C20H17N9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tyk2-IN-8Tyk2-IN-8 (compound 10) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain with an IC50 of 17 nM, used in the treatment of psoriasis[1]. |
| Name | Tyk2-IN-8 |
|---|---|
| Synonym | More Synonyms |
| Description | Tyk2-IN-8 (compound 10) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain with an IC50 of 17 nM, used in the treatment of psoriasis[1]. |
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| Related Catalog | |
| Target |
IC50: 17 nM (TYK2 JH1)[1] |
| In Vitro | Tyk2-IN-8 also inhibits JAK1 (IC50=74 nM) and JAK2 (IC50=383 nM)[1]. |
| References |
| Density | 1.46±0.1 g/cm3(Predicted) |
|---|---|
| Molecular Formula | C20H17N9 |
| Molecular Weight | 383.41 |
| MFCD32197240 |